Journal of Ayurveda Medical Sciences,2017,2,3,244-246.
Introduction: Kshara Kalpana is one of the prominent and widely practiced dosage form of Ayurveda. Varied descriptions regarding the method of preparation are available in different classics. Sushruta Samhita mentions the use of either Jala or Gomutra as the solvent. With these facts in place the present study was conducted to find the differences between the two samples. The aim of the study was to prepare two samples of Apamarga Kshara in presence of Jala (AKJ) and Gomutra (AKG) respectively and to do the physico-chemical analysis of the two samples. Methods: The preparation of AKJ and AKG samples were carried out by following the method as mentioned in Sushruta Samhita. Two samples were analysed on parameters like organoleptic characters, loss on drying, total ash, water soluble ash, acid insoluble ash, pH, water soluble extractive and alcohol soluble extractive. Results: The loss on drying value for AKJ and AKG were 10.63% and 4.54% respectively. Total ash values of AKJ and AKG were 93.21% and 80.54% respectively. Both the samples had pH value of 10 and 100% water soluble extractive value. The values for alcohol soluble extractive for AKJ and AKG were 2.425 and 15.47% respectively. The results obtained from the study showed that both the samples have peculiar characteristics which are in accordance with the properties of Kshara. Conclusion: The study proved that pharmaceutical processing of the raw drugs imparts characteristic properties to the formulation which are evident by the physico-chemical analysis of the two samples.